Specifications
- Antibody type:Primary
- Antigen name:Caspase 12
- Antigen symbol:CASP12
- Clonality:Monoclonal
- Clone:12G6
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- Host:Rat
- Isotype:IgG1 kappa
- Reactivity:Mouse
- Western blot:Yes
- Form:Liquid
- Gene ID:12364
- Antigen synonyms:CASP12P1|CASP-12
- Storage buffer:In PBS containing 0.02% sodium azide.
- Storage temperature:Stable for at least 1 year after receipt when stored at -20˚C.
- Concentration:1 mg/ml
- Shipping temperature:-20°C
- Immunogen:Recombinant mouse caspase-12 (p20 fragment) and synthetic peptide corresponding to aa 183-205 of mouse caspase-12.
- Tested applications:FACS,
- Purification:>95% (SDS-PAGE)
- Size:100 μg
- Pk:100 µG
Specifications
About this item
Caspase-12 is a member of the ICE/CED-3 family of caspases and is detected as a protein of ~51kDa. Overexpression of caspase-12 in cells induces apoptosis. Capase-12 is localized to the endoplasmatic reticulum (ER) and activated by ER stress and specifically cleaves and activates pro-caspase-9 and is also thought to be involved in the apoptosis induced by viral infection. Caspase-12-deficient mice are resistant to ER stress-induced apoptosis. Caspase-12 is probably expressed in many and perhaps all mouse tissues and is expressed at high levels in skeletal muscle, heart, lung and kidney and at moderate levels in brain and liver. In many humans caspase-12 is a pseudo gene and not expressed.
Type: Primary
Antigen: CASP12
Clonality: Monoclonal
Clone: 12G6
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG1 kappa
Reactivity: Mouse
Supplier: VWR Chemicals
Supplier: HEATHROW
Supplier: KIMBERLY CLARK
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: Merck
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection