Anti-ALOX15B Rabbit Polyclonal Antibody (Alexa Fluor® 647)

BOSSBS-6335R-A647

Anti-ALOX15B Rabbit Polyclonal Antibody (Alexa Fluor® 647)

BOSSBS-6335R-A647

Antibody type:
Primary
Antigen name:
Arachidonate 15-Lipoxygenase Type B
Antigen symbol:
ALOX15B
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 647
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
247
Antigen synonyms:
15-LOX-2
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Immunogen:
5-55/676
Purification:
Purified by Protein A
Pk:
100 µl

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ALOX15B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human