Anti-SETD7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog # BOSSBS-6191R-HRP

Supplier: Bioss

Catalog # BOSSBS-6191R-HRP

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
SET Domain Containing 7
Antigen symbol:
SETD7
Clonality:
Polyclonal
Conjugation:
HRP (Horseradish Peroxidase)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Cross adsorption:
No
Form:
liquid
Gene ID:
80854
Antigen synonyms:
histone H3-lysine 4-specific methyltransferase|KIAA1717|lysine N-methyltransferase 7|histone-lysine N-methyltransferase SETD7|KMT7|SET7/9|H3-K4-HMTase SETD7|SET domain-containing protein 7|SET9|SET7|FLJ21193|histone H3-K4 methyltransferase SETD7
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: SETD7
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat