- Antibody type:Primary
- Antigen name:Paxillin Ser178
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:
- Western blot:Yes
- Environmentally Preferable:
- Form:Liquid
- Gene ID:5829
- Antigen synonyms:p-Paxillin Ser178|PAX 1|PAX1|PXN protein|PXNphospho S178|PAXI_HUMAN|Paxillin phospho S178|Paxillin|Paxillin alpha|Paxillin phospho Ser178|FLJ23042|FLJ16691|PXN|Paired box protein Pax 1
- Modification:Phosphorylation (Ser178)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:65 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human Paxillin around the phosphorylation site of Ser178
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).
Type: Primary
Antigen: Paxillin Ser178
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity:
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection