Anti-STAT3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog # BOSSBS-3429R-A647

Supplier: Bioss

Catalog # BOSSBS-3429R-A647

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Signal Transducer And Activator of Transcription 3
Antigen symbol:
STAT3
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 647
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
6774
Antigen synonyms:
Phospho-Signal Transducers and Activators of Transcription 3|pY705|AW109958|signal transducer and activator of transcription 3|ADMIO|Aprf|HIES|APRF
Modification:
phospho-Ser727
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Immunogen:
710-740/770
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: STAT3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat