Anti-SUMO 1 Rabbit Polyclonal Antibody (Cy5®)

Catalog # BOSSBS-1499R-CY5

Supplier: Bioss

Catalog # BOSSBS-1499R-CY5

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
SUMO 1
Clonality:
Polyclonal
Conjugation:
Cy5®
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Rat,
Mouse
Western blot:
Yes
Epitope:
21-101/101
Form:
Liquid
Gene ID:
7341
Antigen synonyms:
Sentrin|UBL1|Ubiquitin-like protein UBL1|SMT3H3|SUMO1|Smt3C|GAP-modifying protein 1|SMT3C|SUMO-1|SMT3 homolog 3|GMP1|OK/SW-cl.43|Small ubiquitin-related modifier 1|Ubiquitin-like protein SMT3C|Ubiquitin-homology domain protein PIC1
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Molecular weight:
12 kDa
Storage temperature:
Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human SUMO 1
Tested applications:
ICC
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.

Type: Primary
Antigen: SUMO 1
Clonality: Polyclonal
Clone:
Conjugation: Cy5
Public Immunogen Range: 21-101/101
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat