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Anti-FosB Ser27 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-FosB Ser27 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13198R-A750
Supplier:  Bioss
Anti-FosB Ser27 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13198R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    FosB Ser27
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    2354
  • Antigen synonyms:
    Oncogene FOS B|FBJ osteosarcoma oncogene B|MGC42291|DKFZp686C0818|fosB|GOSB| Oncogene FOS B|GOS B|p-Fos B phospho S27|G0S3|G0/G1 switch regulatory protein 3|GOS3|Protein fos B|Fos B phospho S27|p-FosB phospho S27|Oncogene FOSB|FOSB_HUMAN|FBJ murine osteosarcoma viral oncogene homolog B|FOS-B|GOS 3|FOS B|FosB|Protein fosB
  • Modification:
    Phosphorylation (Ser27)
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    36 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human Fos B around the phosphorylation site of Ser27
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Type: Primary
Antigen: FosB Ser27
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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