Anti-FOSB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog # BOSSBS-13198R-A555

Supplier: Bioss

Catalog # BOSSBS-13198R-A555

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
FBJ murine osteosarcoma viral oncogene homolog B
Antigen symbol:
FOSB
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 555
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
2354
Antigen synonyms:
AP-1|GOSB|G0S3|GOS3
Modification:
phospho-Ser27
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: FosB
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat