- Antibody type:Primary
- Antigen name:CRTC3/TORC3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:151-260/619
- Form:Liquid
- Gene ID:64784
- Antigen synonyms:TORC3|FLJ21868|CRTC 3|Transducer of regulated cAMP response element-binding protein 3|TORC 3|TORC-3|Transducer of CREB protein 3|Transducer of regulated CREB protein 3|CRTC3_HUMAN|CREB regulated transcription coactivator 3|CREB-regulated transcription coactivator 3|Transducer of regulated cAMP response element binding protein CREB 3|CRTC3|Transducer of regulated cAMP response element binding protein 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:67 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CRTC3/TORC3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC Signalling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
Type: Primary
Antigen: CRTC3/TORC3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 151-260/619
Host: Rabbit
Isotype: IgG
Reactivity: