4408 Results for: "TCS+JNK+5a&amp"

Supplier: Apollo Scientific

MAPK/ERK Signalling Pathway

Supplier: ENZO LIFE SCIENCES

Thienylnaphthamide compound. Potent inhibitor of JNK2 (pIC50=6.5) and JNK3 (pIC50=6.7) targeting the ATP-binding site. Has no activity against JNK1.

Supplier: ProSci Inc.

2'-PDE is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2'-PDE also cleaves 3',5'-phosphodiester bond of oligoadenylates. 2'-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

Supplier: ProSci Inc.

HINT1 Antibody: Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.

Supplier: Apollo Scientific

MAPK/ERK Signalling Pathway

Supplier: Apollo Scientific

MAPK/ERK Signalling Pathway

Supplier: Apollo Scientific

(-)-(5aS,10bR)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium chloride monohydrate

Supplier: Merck

AMP (2-Amino-2-methylpropanol) for synthesis, Sigma-Aldrich®

Supplier: TCI

cis-Decahydro-1H,6H-3a,5a,8a,10a-tetraazapyrene ≥98.0% (by GC)

Supplier: Cayman Chemical

HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC₅₀= 6 nM) that poorly blocks other HDAC enzymes.

Supplier: VWR Chemicals

5% water has been added to maintain liquidity at room temperature.

Supplier: TCI

(-)-(5aS,10bR)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium chloride monohydrate ≥98.0% (by HPLC)

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus NS3 Genotype-5a

Supplier: Bioss

Anti-DH-5A Rabbit Polyclonal Antibody

Supplier: Abcam

Anti-Semaphorin 5A Goat Polyclonal Antibody

Supplier: Everest Biotech

Anti-Semaphorin 5A Goat Polyclonal Antibody

Supplier: US Biological

Anti-STAT 5a Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Semaphorin 5A Goat Polyclonal Antibody

Supplier: US Biological

Anti-STAT 5a Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Semaphorin 5A Rabbit Polyclonal Antibody (Biotin)

Supplier: TCI

(+)-(5aR,10bS)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium chloride monohydrate ≥98.0% (by HPLC)

Supplier: US Biological

Anti-STAT 5a Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Semaphorin 5A Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Semaphorin 5A Sheep Polyclonal Antibody

Supplier: US Biological

Anti-Semaphorin 5A Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Stat 5a Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Supplier: US Biological

Anti-Semaphorin 5A Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: US Biological

Anti-Serotonin Receptor 5A Rabbit Polyclonal Antibody

Supplier: Merck

Molecular sieve A5 (0.5 nm, 5 Å) Moisture Trap volume 200 cc, 1/4 in. fitting, Supelco®

Supplier: Merck

Molecular sieve A5 (0.5 nm, 5 Å) Moisture Trap volume 200 cc, 1/8 in. fitting, Supelco®