"Stemcell Technologies"

Supplier: Stemcell Technologies

Medium for maintenance and expansion of neural progenitor cells derived from human ES and iPS cells.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse, hamster CD4, PerCP-Cy5.5-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1, kappa isotype control antibody, unconjugated.

Supplier: Stemcell Technologies

Modulate prostaglandin metabolism with 15-hydroxyprostaglandin dehydrogenase (15-PGDH). 15-PGDH catalyses the reversible oxidation of the 15-hydroxyl group in prostaglandins, resulting in inactivated metabolites (Ensor and Tai), it can act on a variety of prostaglandins as substrates in a NAD+ dependent manner (Cho et al.). As prostaglandins can have a range of effects on cellular processes, 15-PGDH is of considerable importance in drug development. In vitro and in vivo studies suggest 15-PGDH has tumor suppressive activity and is downregulated in certain cancers (Na et al.).15-PGDH belongs to the short-chain dehydrogenases/reductases (SDR) family; its primary structure indicates 20% homology with other SDRs, with some conserved amino acid residues (Krook et al.). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, apo M from STEMCELL comes lyophilised with ≥89% purity.

Supplier: Stemcell Technologies

Medium for thawing and culturing hPSC-derived cardiomyocytes.

Supplier: Stemcell Technologies

For reverse transcription of eukaryotic mRNA before qPCR or RNA sequencing.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD34, unconjugated.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse CD127, APC-conjugated.

Supplier: Stemcell Technologies

Goat polyclonal antibody against rabbit IgG (H+L).

Supplier: Stemcell Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf and Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilization of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Mouse G-CSF was first purified from cultures of the WEHI-3B myelomonocytic leukemia cell line as the inducer of the terminal differentiation of WEHI-3B and other myeloid leukemia cell lines (Nicola et al.). It was later cloned in monkey COS cells from a cDNA library prepared with mRNA derived from mouse fibrosarcoma NFSA cells that produce G-CSF constitutively (Tsuchiya et al.). Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Supplier: Stemcell Technologies

Immunodensity isolation of untouched plasma cells for multiple myeloma research.

Supplier: Stemcell Technologies

Mouse monoclonal antibody against human CD154 (CD40L).

Supplier: Stemcell Technologies

The EasySep™ 'The Big Easy' magnet is designed for cell separation procedures using EasySep™ reagents when processing a large number of cells, or when using RoboSep™.

Supplier: Stemcell Technologies

Base methylcellulose medium for mouse cells.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human leukocytes from whole blood.

Supplier: Stemcell Technologies

For culture and evaluation of mouse mammary epithelial cells.