2606 Results for: "SR-12813&amp"

Supplier: Bioss

AMP deaminase plays a critical role in energy metabolism.

Supplier: Avantor Fluid Handling

Operate a 230-240 VAC motor with only a 115 VAC power supply.

Supplier: Bioworld Technology

Synthetic peptide, corresponding to amino acids N-terminus of Human SR-5A.

Supplier: KNF

In addition to the features of the base pumps, you will have the ability to extend the pump to a system with separators and a high-performance condenser. This allows for environmentally friendly recovery of solvents with excellent protection against aggressive chemicals.

Supplier: Apollo Scientific

Adenosine 5'-monophosphate disodium salt (from yeast)

Supplier: Brady

This fuse lockout device has been designed to prevent the unintended re-energisation of an energy source through a fuse. The device fits most fuse holders between 20 Amps and 400 Amps.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Thermo Fisher Scientific

Strontium bromide hexahydrate ≥95%

Supplier: US Biological

Anti-SR-A1, Serine/Arginine-Rich pre-mRNA Splicing Factor Rabbit Polyclonal Antibody

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Bioss

SR-A1 (serine arginine-rich pre-mRNA splicing factor) is a member of the SR protein family, which interacts with the C-terminal domain of the large subunit of RNA polymerase II and involved in pre-mRNA splicing. The SR-A1 gene is located on chromosome 19q13.3-q13.4. Overexpression of SR-A1 is found in aggressive ovarian cancers.

Supplier: Merck

Strontium Standard, 1000 mg/L, Certipur®, Supelco®, Strontium, Matrix: Nitric acid dil., Application: ICP standards

Supplier: Bioss

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

Supplier: Bioss

Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.

Supplier: Bioss

Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.

Supplier: ENZO LIFE SCIENCES

Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

Supplier: Abcam

Anti-SR protein repeat/SRSF6 Rabbit Monoclonal Antibody [clone: EPR9231]

Supplier: Bioss

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the Signalling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Supplier: Bioss

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the Signalling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Supplier: Bioss

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the Signalling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Supplier: Bioss

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the Signalling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Supplier: Bioss

The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the Signalling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.