98 Results for: "PRECISION DYNAMICS"
Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
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Anti-INPPL1 Rabbit Polyclonal Antibody
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
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Anti-INPPL1 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
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Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalisation and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Expand 1 Items
Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Expand 1 Items
Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
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Precision balances, Adventurer®
Supplier: OHAUS
A range of balances with multiple features, but uncomplicated weighing capabilities, provide the user with rapid, accurate results for routine weighing and measurement activities. Applications include weighing, formulation, dynamic weighing, parts counting, totalisation, density determination, check weighing and percentage weighing. Stabilisation times are typically less than two seconds.
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DX4™ Softshell Jackets
Supplier: Portwest
The DX4 Softshell jacket is precision engineered using a revolutionary breathable, waterproof, and windproof ripstop fabric. Its sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims, and multiple secure pockets for ample storage. An ideal choice for the modern worker.
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Softshell jackets, DX4™, DX474
Supplier: Portwest
The DX4™ Softshell Jackets are precision engineered using a revolutionary breathable, waterproof and windproof ripstop fabric. These sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims and multiple secure pockets for ample storage. An ideal choice for the modern worker.
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Immersion thermostats, MAGIO™ MS and MX
Supplier: JULABO GmbH
The MAGIO™ series of bridge mounted circulators operate with a working temperature range of −50 to +300 °C* and a heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ immersion thermostats can be adapted to different tanks and applications.
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Western blotting detection reagent, Amersham™ ECL™ Prime
Supplier: Cytiva
Amersham™ ECL™ Prime is a highly sensitive Western blotting detection reagent characterised by stable signal emission, allowing for the possibility of repeated exposures and making it easier to process several blots in the same experimental run. Amersham™ ECL™ Prime delivers a detection system that is sensitive, stable, precisely quantitative across a wide dynamic range of protein levels, and conservative in its consumption of expensive antibody reagents. The high performance of Amersham™ ECL™ Prime is due to the presence of an enhancer in the reagent, increasing enzyme turnover, and thereby significantly increasing both signal intensity and duration. The light signal is further intensified by the addition of a catalyst.
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Heating and cooling process thermostats, Integral XT
Supplier: LAUDA
Process thermostats with integrated cooling system for dynamic temperature control within external circuits.
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MediLine, laboratory refrigerators, compact
Supplier: Liebherr
These MediLine laboratory refrigerators with Comfort controller provide maximum storage space on a 60 cm wide footprint. The under bench models are 820 mm high and will fit under almost any laboratory bench. These appliances meet the exacting demands made of laboratory refrigeration.
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Labelling tapes for anesthesia drug syringes
Supplier: PRECISION DYNAMICS TIMEM
Coated paper tape with removable adhesive. The following user applied drug tapes are available for accurate and reliable labelling of all anesthesia drug syringes. This specification covers the size, colour, pattern, and type used on labels applied to unlabelled syringes, filled by the users or their agents, to identify the drug content. In addition, tapes correspond to the published 2004 JCAHO Standard MM,4,30 for appropriately labelling all medications with drug name, strength, amount, expiration date, expiration time, and initials of the person administering the medication.
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Heating and cooling process thermostats, Integral T
Supplier: LAUDA
Integral T are process thermostats with an integrated cooling system for dynamic temperature control within external circuits.
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Heating circulators, MAGIO™ MS and MX series
Supplier: JULABO GmbH
The MAGIO™ series of heating circulators operate with a working temperature range of 20 to +300 °C and heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ circulators can be modularly and individually adapted to applications.
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Refrigerated and heating circulators, MAGIO™ MS series
Supplier: JULABO GmbH
The MAGIO™ series of cooling and heating circulators operate with a working temperature range of –50 to +300 °C and heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ circulators can be modularly and individually adapted to applications.
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Temperature control systems, PRESTO®
Supplier: JULABO GmbH
PRESTO® systems cover a working temperature range of −93 to +250 °C with high cooling and heating capacity. These instruments can compensate for exothermic and endothermic reactions with extraordinary speed, they feature high flow rates, constant pressure and a controlled build-up of pump pressure. Changes in the temperature control of liquid viscosity are balanced dynamically. Permanent internal monitoring and self-lubricating pumps contribute to long service life. The integrated touch panel gives the user a clear view of important information. Fingertip control via the touch screen. Multiple interfaces enable remote control of the PRESTO® across networks and in super-ordinated control systems. Wireless remote control of the new PRESTO® can easily be done by using the Wireless TEMP range of products.
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LABEL ATIVAN 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL ATIVAN 1 * 1 Roll
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LABEL STADOL 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL STADOL 1 * 1 Roll
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LABEL NIFEDIPINE 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL NIFEDIPINE 1 * 1 Roll
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LABEL DOPRAM 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL DOPRAM 1 * 1 Roll
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LABEL HYDRALAZINE 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL HYDRALAZINE 1 * 1 Roll
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LABEL METOCURINE 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL METOCURINE 1 * 1 Roll
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RIBBON RADIOACTIVE 12,7MM 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
RIBBON RADIOACTIVE 12,7MM 1 * 1 Roll
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LABEL SCOPOLAMINE 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL SCOPOLAMINE 1 * 1 Roll
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LABEL VERAPAMIL 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL VERAPAMIL 1 * 1 Roll
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LABEL BUTORPHANOL 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
LABEL BUTORPHANOL 1 * 1 Roll
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RIBBON PERSONNALISED ALPHA 2 1 * 1 Roll
Supplier: PRECISION DYNAMICS TIMEM
RIBBON PERSONNALISED ALPHA 2 1 * 1 Roll
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RIBBON CONTAMINATED 1 * 1 items
Supplier: PRECISION DYNAMICS TIMEM
RIBBON CONTAMINATED 1 * 1 items