"Other Essentials"

Supplier: ProSci Inc.

SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.

Supplier: ProSci Inc.

CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Supplier: Avantor

The quality of many BAKER ANALYZED™ Reagents meets or exceeds the requirements set forth by the American Chemical Society (ACS). These solvents are essential for any chemical stockroom.

Supplier: MERCK PRODUCTION CHEMICALS

Lactose monohydrate, powder, EMPROVE® EXPERT BP, Ph. Eur., JP, NF suitable for use as excipient, SAFC®

Supplier: Merck

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques. Tepraloxydim CRM may also be used as given below:

Supplier: ENTEGRIS

These 100 mm wafer carriers are designed for optimum performance in automated operations or for processing LCDs and other small devices.

Supplier: Abcam

Leukotriene B4 ELISA kit is a ELISA kit for the measurement of Leukotriene B4 in plasma, serum, Other biological fluids samples.

Supplier: AAT Bioquest

Cy3® dye is one of the most common cyanine dyes used for labeling proteins, nucleic acids and other biological molecules.

Supplier: MERCK PRODUCTION CHEMICALS

Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph. Eur., BP, USP, FCC

Supplier: Bioss

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Abcam

Nonhydrolyzable GTP analog. Modulates G-protein cell signaling, protein synthesis and other metabolic processes. Forms stable protein complexes.

Supplier: Abcam

Lysozyme ELISA kit is a Sandwich (quantitative) ELISA kit for the measurement of Lysozyme in Human in serum, Other biological fluids samples.

Supplier: AAT Bioquest

SoNa™ 520 is a new sodium-sensitive fluorescent indicator dye used to detect sodium levels in cells and other biological samples.

Supplier: AAT Bioquest

Cy3® dye is one of the most common cyanine dyes used for labeling proteins, nucleic acids and other biological molecules.

Supplier: G-Biosciences

E-64 is an irreversible inhibitor of cysteine proteases. It interacts with the Sn subsites of proteases but has no action on cysteine residues in other proteins.

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.