9711 Results for: "Acridine-3,6-diamine&amp"

Supplier: Biotium

NAO is a green fluorescent mitochondrial dye whose staining is not dependent on mitochondrial membrane potential.

Supplier: TCI

3,6-Diaminocarbazole ≥98.0% (by titrimetric analysis)

Supplier: Apollo Scientific

3-Bromobenzene-1,2-diamine, Technical Grade

Supplier: Apollo Scientific

4-Bromo-5-iodobenzene-1,2-diamine 95%

Supplier: Apollo Scientific

Mono(boc)(PEO)-3-diamine, boc-DOOA 98%

Supplier: TCI

Mono(boc)(PEO)-3-diamine, boc-DOOA ≥97.0% (by HPLC)

Supplier: TCI

2,3,5,6-Tetramethyl-m-phenylenediamine ≥98.0% (by GC, titration analysis)

Supplier: TCI

Biotin-PEG2-Amine ≥98.0% (by HPLC)

Supplier: Apollo Scientific

N-Boc-N-methyl-1,3-diaminopropane

Supplier: Apollo Scientific

Biotin-PEG2-Amine

Supplier: Merck

Ethylenediammonium sulphate ≥97% for synthesis, Sigma-Aldrich®

Supplier: TCI

4,4',4''-Tris(diphenylamino)triphenylamine ≥97.0% (by HPLC, total nitrogen)

Supplier: TCI

Ethylenediammonium sulphate ≥98.0% (by titrimetric analysis)

Supplier: SIGMA ALDRICH MICROSCOPY

Trypan Blue (C.l. 23850) is a large, tetrasulfonated anionic, hydrophilic dye. It is also known as diamine blue 3B. Trypan blue has been used as a dye in trypan blue exclusion assay/cell viability assay to detect dead cells.

Supplier: Apollo Scientific

Acridine

Supplier: SIGMA ALDRICH MICROSCOPY

Acridine is a small cationic and planar dye that mainly binds to RNA and DNA. These dyes are strongly fluorescent. It resembles the structure of xanthene except that the heteroatom is nitrogen, not oxygen. Acridine is suitable for nucleic acid staining, particularly for cell cycle determination. Acridines are used as fluorescent materials for visualisation of biomolecules, and in laser technologies.

Supplier: AAT BIOQUEST

This thiol-reactive biotin derivative contains a long arm (~20 angstrom) to increase its avidin-binding affinity.

Supplier: TCI

9-(Bromomethyl)acridine ≥98.0% (by HPLC, titration analysis) for HPLC labeling

Supplier: TCI

Acridine ≥98.0% (by HPLC, titration analysis)

Supplier: Apollo Scientific

Acridine-9-carboxylic acid

Supplier: Thermo Fisher Scientific

Acridine ≥97%

Supplier: Biotium

The amine reactive succinimidyl ester of green fluorescent AO (acridine orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates then are able to complex with nucleic acids, resulting in green fluorescence nucleic acid conjugate adduct, making them potentially useful for studies of nucleic acid binding to various biomolecules, such as DNA-binding proteins.

Supplier: Apollo Scientific

8H-Indolo[3,2,1-de]acridin-8-one 99%

Supplier: TCI

10H-Spiro[acridine-9,9'-fluorene] ≥98.0% (by HPLC, total nitrogen)

Supplier: TCI

Acridinium chloride ≥98.0% (by HPLC, titration analysis)

Supplier: AAT BIOQUEST

This carbonyl-reactive biotin derivative contains a long arm (~20 Å) increase its avidin-binding affinity.

Supplier: Thermo Fisher Scientific

9-Acridone ≥99%

Supplier: Apollo Scientific

4-Acridinecarboxylic acid ≥98%

Supplier: Bioss

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2.

Supplier: Bioss

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively. Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3. AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160. Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A. Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2.