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106663 results for "4-Carboxyphenylboronic acid pinacol ester&amp"

106663 Results for: "4-Carboxyphenylboronic acid pinacol ester&amp"

Anti-PPAPDC1B Rabbit Polyclonal Antibody

Anti-PPAPDC1B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

PPAPDC1B Antibody: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.

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Gentle Collagenase/Hyaluronidase

Gentle Collagenase/Hyaluronidase

Supplier: STEMCELL TECHNOLOGIES

10X Gentle collagenase/hyaluronidase in DMEM.

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Human ACD full-length ORF ( AAH16904, 1 A.A. - 544 A.A.) Recombinant protein with GST-TAG AT N-terminal. 1 * 25 G

Supplier: Abnova

Human ACD full-length ORF ( AAH16904, 1 A.A. - 544 A.A.) Recombinant protein with GST-TAG AT N-terminal. 1 * 25 G

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Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Anti-GABBR2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Recombinant protein, acd( aah16904, 1 a.a. - 545 a.a.) full-length recombinant protein with gst tag. 1 * 10 µG

Supplier: Abnova

Recombinant protein, acd( aah16904, 1 a.a. - 545 a.a.) full-length recombinant protein with gst tag. 1 * 10 µG

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DNase I

DNase I

Supplier: STEMCELL TECHNOLOGIES

For digestion of DNA.

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Multi-position magnetic hotplate stirrers

Multi-position magnetic hotplate stirrers

Supplier: witeg Labortechnik

Digital multi-position magnetic stirrer ideal for mixing and heating simultaneously. Ideal for heat sensitive procedures in microbiology, biochemistry or sample drying. Units feater a powder-coated steel body which is easy to clean. Each plate can accommodate a support rod.

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Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Cleanroom gloves, latex, BioClean Legacy™

Cleanroom gloves, latex, BioClean Legacy™

Supplier: Nitritex

These ambidextrous cleanroom gloves with beaded cuffs can be used in medical as well as in laboratory environments. Suitable for double-donning.

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α-Amylase Inhibitor Screening Kit

α-Amylase Inhibitor Screening Kit

Supplier: Abcam

Simple, 1-step assay for screening potential α-amylase inhibitors.

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Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Cleanroom gloves, latex, BioClean Legend™

Cleanroom gloves, latex, BioClean Legend™

Supplier: Nitritex

These hand-specific cleanroom gloves with beaded cuffs can be used in medical as well as in laboratory environments.

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Micro pipetting aid ''micro-classic'' with suction tube and adapter, for micro-pipettes and other pipettes up to 1 ml 1 * 1 items

Supplier: GLASWARENFABRIK KARL HECHT

Micro pipetting aid ''micro-classic'' with suction tube and adapter, for micro-pipettes and other pipettes up to 1 ml 1 * 1 items

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Polyester Tapes, 8901

Polyester Tapes, 8901

Supplier: 3M

Thin and conformable, 3M™ polyester tape 8901 excels in high temperature masking operations such as powder coat painting. Coated with a silicone adhesive, this tape bonds to a variety of difficult surfaces. It is chemical-resistant and performs under a wide range of temperatures and environments.

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Cleanroom gloves, latex, BioClean Legion™

Cleanroom gloves, latex, BioClean Legion™

Supplier: Nitritex

These ambidextrous cleanroom gloves with beaded cuffs can be used in medical as well as in laboratory environments.

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Cleanroom gloves, latex, sterile, BioClean Alpha™

Cleanroom gloves, latex, sterile, BioClean Alpha™

Supplier: Nitritex

These latex gloves with beaded cuffs are hand-specific and anatomically shaped.

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Tangential flow filtration systems and capsules, Minimate™ EVO

Tangential flow filtration systems and capsules, Minimate™ EVO

Supplier: Cytiva (Formerly Pall Lab)

Reusable TFF devices and system for bioprocessing applications that accelerates and simplifies processing of up to 1 L.

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Anti-GABBR2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

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Human Amyloid Beta 42 ELISA Kit

Human Amyloid Beta 42 ELISA Kit

Supplier: Abcam

An Sandwich ELISA kit for quantifying human amyloid beta 42 alpha in biological fluids.

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Cleanroom gloves, latex, sterile, BioClean Advance™

Cleanroom gloves, latex, sterile, BioClean Advance™

Supplier: Nitritex

These hand-specific latex gloves are anatomically shaped and therefore comfortable to wear. They can be used in medical areas as well as in laboratories.

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One-Step Blue® protein gel stain

One-Step Blue® protein gel stain

Supplier: Biotium

One-Step Blue® is a ready-to-use protein gel staining solution. It produces fast (5-60 min) protein staining in a single step without fixation or washing.

   Sustainable Options Available
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Rat Recombinant VEGF-165 (from E. coli)

Rat Recombinant VEGF-165 (from E. coli)

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

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Scrubber, KS 1000

Scrubber, KS 1000

Supplier: VELP SCIENTIFIC

Designed to neutralise toxic fumes produced during mineralisation and safeguard lab operators without requiring any connection to tap water.

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Anti-RAE1 Rabbit Polyclonal Antibody

Anti-RAE1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Anti-RAE1 Rabbit Polyclonal Antibody

Anti-RAE1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly (A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Industrial scales, Valor® 4000

Industrial scales, Valor® 4000

Supplier: OHAUS

Waterproof compact scales designed for the food industry. Features include keypad with four mechanical switches, adjustable feet, level bubble and cover with spring to protect power connector of the scale from ingress of moisture, especially when the scale is washed down. Dual LED display back and front enable two operators to work with the Valor® 4000 at the same time.

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Human IL-2 ELISA Kit (High Sensitivity)

Supplier: ANTIBODIES.COM

Human IL-2 ELISA kit is a high sensitivity sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL-2 in serum, plasma, and other biological fluids.

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Mouse IL-10 ELISA Kit (High Sensitivity)

Supplier: ANTIBODIES.COM

Mouse IL-10 ELISA kit is a high sensitivity sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse IL-10 in serum, plasma, and other biological fluids.

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