108 Results for: "2,3-Dichlorophenyl isothiocyanate&amp"

Supplier: Bioss

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

Supplier: Biorbyt

Anti-MMP-23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Abcam

Anti-CD40 Rat monoclonal antibody FITC (Fluorescein) [clone: 3/23]

Supplier: Bioss

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

Supplier: Biorbyt

Anti-FGF23 Rabbit Polyclonal Antibody (RBITC)

Supplier: Biorbyt

Anti-TTC23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-C12orf23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-CCDC23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-KLHL23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-BPGM Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-ZNF23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-ADAM23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-IL23R Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-CDC23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-FGF23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Biorbyt

Anti-KIF23 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Bioss

In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1 (2). CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits (3). Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS (4). CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins (2,5). CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription (6,7).

Supplier: Bioss

C9orf23 (chromosome 9 open reading frame 23) is a 163 amino acid protein that belongs to the histone-like Alba family and is encoded by a gene that maps to human chromosome 9p13.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.