BIX 01294 trihydrochloride, hydrate ≥85.0% (by total nitrogen basis)
Supplier: TCI
BIX 01294 trihydrochloride, hydrate ≥85.0% (by total nitrogen basis)
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BIX 01294 trihydrochloride, hydrate ≥95% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Selective and cell permeable inhibitor of G9a histone methyltransferase.
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(5S)-3,4,5,6-Tetrahydro-5-phenyl-N-(benzyloxycarbonyl)-4(H)-1,4-oxazin-2-one
Supplier: Apollo Scientific
(5S)-3,4,5,6-Tetrahydro-5-phenyl-N-(benzyloxycarbonyl)-4(H)-1,4-oxazin-2-one
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UNC0224 98%
Supplier: Apollo Scientific
UNC0224 is a selective inhibitor of G9a with IC50 of 15 nM.
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Compound E ≥95% (by HPLC) Calbiochem®, Sigma-Aldrich®
Supplier: Merck Millipore (Calbiochem)
A cell-permeable, potent, selective, peptidomimetic, non-transition-state analog inhibitor of γ-secretase and Notch processing (IC₅₀=300 pM for Aβ₄₀ in CHO cells overexpressing wild type βAPP; 240 pM for Aβ₄₀, 370 pM for Aβ₄₂, and 320 pM for NICD, respectively, in HEK293 cells stably transfected with βAPP₆₉₅
and mNotchδE; 100 pM for both Aβ₄₀ and Aβ₄₂ in SH-SY5Y cells stably transfected with SPA4CT).
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3,4-Dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
Supplier: Apollo Scientific
3,4-Dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
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5-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one ≥98%
Supplier: Apollo Scientific
5-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one ≥98%
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1-[1-Phenyl-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl]pentan-1-one ≥98.0% (by HPLC)
Supplier: TCI
1-[1-Phenyl-3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl]pentan-1-one ≥98.0% (by HPLC)
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6,7-Dihydro-2-(2,4,6-trimethylphenyl)-5H-pyrrolo[2,1-c]-1,2,4-triazolium perchlorate
Supplier: Apollo Scientific
6,7-Dihydro-2-(2,4,6-trimethylphenyl)-5H-pyrrolo[2,1-c]-1,2,4-triazolium perchlorate
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2-(4-Methylhomopiperazin-1-yl)benzyl alcohol 97%
Supplier: Apollo Scientific
2-(4-Methylhomopiperazin-1-yl)benzyl alcohol 97%
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3-Methyl-3H-benzo[d][1,2]diazepin-4(5H)-one ≥98%
Supplier: Apollo Scientific
3-Methyl-3H-benzo[d][1,2]diazepin-4(5H)-one ≥98%
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1-[4-(1H-Pyrazol-5-yl)phenyl]-1,4-dihydropyridin-4-one 95%
Supplier: Apollo Scientific
1-[4-(1H-Pyrazol-5-yl)phenyl]-1,4-dihydropyridin-4-one 95%
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4-Methyl-5,6,7,8-tetrahydro-2(1H)-quinolinone 95%
Supplier: Apollo Scientific
4-Methyl-5,6,7,8-tetrahydro-2(1H)-quinolinone 95%
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6,7-Dihydro-2-(2,4,6-trimethylphenyl)-5H-pyrrolo[2,1-c]-1,2,4-triazolium perchlorate ≥98.0% (by HPLC)
Supplier: TCI
6,7-Dihydro-2-(2,4,6-trimethylphenyl)-5H-pyrrolo[2,1-c]-1,2,4-triazolium perchlorate ≥98.0% (by HPLC)
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4-Methyl-1,5,6,7-tetrahydro-2H-cyclopenta[b]pyridin-2-one 95%
Supplier: Apollo Scientific
4-Methyl-1,5,6,7-tetrahydro-2H-cyclopenta[b]pyridin-2-one 95%
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1-Methyl-1,5,6,7-tetrahydroindazol-4-one 95%
Supplier: Apollo Scientific
1-Methyl-1,5,6,7-tetrahydroindazol-4-one 95%
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Alosetron hydrochloride ≥98.0% (by HPLC)
Supplier: TCI
Alosetron hydrochloride ≥98.0% (by HPLC)
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Pirenzepine dihydrochloride ≥98.0% (by HPLC, titration analysis)
Supplier: TCI
Pirenzepine dihydrochloride ≥98.0% (by HPLC, titration analysis)
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(±)-Evodiamine ≥98.0% (by HPLC, total nitrogen)
Supplier: TCI
(±)-Evodiamine ≥98.0% (by HPLC, total nitrogen)
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Coumarin 102 ≥97.0% (by HPLC, total nitrogen)
Supplier: TCI
Coumarin 102 ≥97.0% (by HPLC, total nitrogen)
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Ondansetron hydrochloride dihydrate 98%
Supplier: Thermo Fisher Scientific
Ondansetron hydrochloride dihydrate 98%
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3-Hydroxy-2-phenyl-4(1H)-quinolinone 95%
Supplier: Apollo Scientific
3-Hydroxy-2-phenyl-4(1H)-quinolinone 95%
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BIX 01294 95%
Supplier: Thermo Fisher Scientific
Chemical probes can be used to help establish the
relationship between a molecular target and the broader
biological consequences of modulating that target in cells
or organisms.
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ML-9 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Selective inhibitor of MLC kinase (Ki=3.8 µM). Inhibits insulin-stimulated 2-deoxyglucose transport and PP-1 activation in adipocytes, possibly via an effect on MAP kinase or its activation. Useful PKB inhibitor (IC50=10-50 µM). Also known to inhibit PKA (IC50=20 µM) and S6 kinase (IC50=50 µM). Does not inhibit PI 3-kinase.
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Molindone hydrochloride ≥98.0% (by HPLC, titration analysis)
Supplier: TCI
Molindone hydrochloride ≥98.0% (by HPLC, titration analysis)
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Ondansetron hydrochloride dihydrate ≥98.0% (by HPLC, titration analysis)
Supplier: TCI
Ondansetron hydrochloride dihydrate ≥98.0% (by HPLC, titration analysis)
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N-Methyl-2-(4-methylhomopiperazin-1-yl)benzylamine 97%
Supplier: Apollo Scientific
N-Methyl-2-(4-methylhomopiperazin-1-yl)benzylamine 97%