ZIC®-cHILIC is based on the same technology platform as ZIC®-HILIC, but has a different functional group and an improved manufacturing procedure. The different charge orientation of the zwitterionic functional group leads to a different – and complementary – selectivity for polar hydrophilic compounds. This selectivity is especially beneficial for hydrophilic compounds that are negatively charged, positively charged, zwitterionic or neutral, for example, organic acids, amino acids, metabolites, aminoglycosides and nucleotides.

• Complementary selectivity by reoriented charges in zwitterionic functional group
• Perfect LC-MS compatibility due to low eluent buffer strengths and very low bleeding
• High density-bonded phosphorylcholine zwitterionic stationary phase
• Very high stability and excellent batch-to-batch reproducibility