Specifications
- Antibody type:Primary
- Antigen name:tumor necrosis factor (ligand) superfamily, member 13b
- Antigen symbol:TNFSF13B
- Clonality:Monoclonal
- Clone:C257/1638
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Mouse
- ImmunoFluorescence:Yes
- Isotype:IgG1
- Reactivity:Human
- Format:Purified Antibody
- Form:Liquid
- Gene ID:Q9Y275
- Antigen synonyms:TNFSF13B
- Storage buffer:PBS with 0,1 mg/ml BSA and 0,05% sodium azide
- Storage temperature:Aliquot and Store at 2…8 °C. Avoid freez-thaw cycles.
- Concentration:0,2 mg/ml
- Shipping temperature:4 °C
- Immunogen:Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
- Purification:Protein G affinity chromatography
- Size:100 µg
- Pk:100 µG
Specifications
About this item
BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
Flow Cytometry: 0,5-1 µg/million cells IF: 1 - 2 µg/ml Titering of the BAFF antibody may be required for optimal performance.
Type: Primary
Antigen: TNFSF13B
Clonality: Monoclonal
Clone: C257/1638
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human