Specifications
- Antibody type:Primary
- Antigen name:tumor necrosis factor
- Antigen symbol:TNF
- Clonality:Monoclonal
- Clone:MAb11
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Cross adsorption:No
- Form:liquid
- Gene ID:P01375
- Antigen synonyms:TNF
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:100 Tests
Specifications
About this item
The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha (TNF-alpha), a 157 amino acid non-glycosylated protein. TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. The MAB11 antibody was generated from recombinant human TNF and is reported to be a neutralizing antibody.
Type: Primary
Antigen: TNF
Clonality: Monoclonal
Clone: MAb11
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human