Specifications
- Antibody type:Primary
- Antigen name:5HT7 Receptor/SR-7
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western blot:Yes
- Epitope:51-150/479
- Form:Liquid
- Gene ID:3363
- Antigen synonyms:5HT7|HT 7|Serotonin 5 HT 7 receptor|5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled|5-HT7|HTR7|5 HT X|Serotonin receptor 7|5-HT-7|5 hydroxytryptamine receptor 7|5HT7R_HUMAN|5-HT-X|5-hydroxytryptamine receptor 7|5 hydroxytryptamine serotonin receptor 7
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:54 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
Type: Primary
Antigen: 5HT7 Receptor/SR-7
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/479
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat