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Anti-EXTL3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-EXTL3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13123R-A750
Supplier:  Bioss
Anti-EXTL3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13123R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    EXTL3
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat
  • Western blot:
    Yes
  • Epitope:
    351-450/919
  • Form:
    Liquid
  • Gene ID:
    2137
  • Antigen synonyms:
    REGR|EXTR1|Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas|botv|RPR|EXTL3_HUMAN|Multiple exostosis-like protein 3|Putative tumor suppressor protein EXTL3|Exostoses multiple-like 3|EXTL1L|Hereditary multiple exostoses gene isolog|KIAA0519|Exostosin-like 3|Exostoses-like 3|EXT-related protein 1|Reg receptor|DKFZp686C2342|EXTL3|REG|Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    105 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human EXTL3
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

Type: Primary
Antigen: EXTL3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 351-450/919
Host: Rabbit
Isotype: IgG
Reactivity: Rat