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Anti-MECP2 Rabbit Polyclonal Antibody
Anti-MECP2 Rabbit Polyclonal Antibody
Catalog # BSENR-1810-100
Supplier:  Biosensis
Anti-MECP2 Rabbit Polyclonal Antibody
Catalog # BSENR-1810-100
Supplier:  Biosensis

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Methyl-CpG binding protein 2 (MeCP2)
  • Antigen symbol:
    MECP2
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Format:
    Purified IgG
  • Form:
    Lyophilized
  • Antigen synonyms:
    MeCp2|MeCp-2 protein
  • Amino acid number:
    471 to 486
  • UniProtKB:
    Uniprot # P51608
  • Sequence:
    REEPVDSRTPVTERVS
  • Storage temperature:
    Store lyophilised antibody at 2-8 °C. After reconstitution divide into aliquots and store at –20 °C for long-term storage. Store at 2-8 °C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
  • Shipping temperature:
    Ambient
  • Immunogen:
    A synthetic peptide (REEPVDSRTPVTERVS, aa: 471-486) of C-terminus of human protein.
  • Purification:
    Affinity purified
  • Size:
    100 µg
  • Pk:
    100 µG

Specifications

About this item

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org

  • Western blotting (1:1,000-1:5,000) and Immunohistochemistry (1:1,000) Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: MECP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat