Anti-MECP2 Rabbit Polyclonal Antibody
Catalog # BSENR-1810-100
Supplier: Biosensis
Specifications
- Antibody type:Primary
- Antigen name:Methyl-CpG binding protein 2 (MeCP2)
- Antigen symbol:MECP2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Format:Purified IgG
- Form:Lyophilized
- Antigen synonyms:MeCp2|MeCp-2 protein
- Amino acid number:471 to 486
- UniProtKB:Uniprot # P51608
- Sequence:REEPVDSRTPVTERVS
- Storage temperature:Store lyophilised antibody at 2-8 °C. After reconstitution divide into aliquots and store at –20 °C for long-term storage. Store at 2-8 °C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
- Shipping temperature:Ambient
- Immunogen:A synthetic peptide (REEPVDSRTPVTERVS, aa: 471-486) of C-terminus of human protein.
- Purification:Affinity purified
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org
- Western blotting (1:1,000-1:5,000) and Immunohistochemistry (1:1,000) Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: MECP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat