The JC Virus BioProbe® labeled probe is prepared by nick translation of a clone of the entire JC virus genome. JC virus, a member of the papovavirus family, usually causes subclinical infections. However, in immunocompromised individuals it can cause a fatal demyelinating brain disease, progressive multifocal leukoencephalopathy. JC virus is also neurooncogenic in primates. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis).