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Mouse recombinant TSLP receptor
Mouse recombinant TSLP receptor
Catalog # PRSI92-533
Supplier:  ProSci Inc.
CAS Number:  
Mouse recombinant TSLP receptor
Catalog # PRSI92-533
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Species:
    Mouse
  • Tag sequence:
    C-Fc tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    TSLP receptor|CRL2|Thymic stromal lymphopoietin protein receptor|CRLM-2|cytokine receptor-like factor 2|Thymic stromal-derived lymphopoietin receptor|TSLPR|CRL2 precusor|Cytokine receptor-like 2|P2RY8/CRLF2 fusion|TSP R|ILXR|PCOR1|CRL2 cytokine receptor|CRLF2|IL-XR|CRLF2Y
  • Protein/peptide name:
    TSLP Receptor
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    49.8 kD
  • Sequence:
    Ala20-Leu233
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common gamma receptor–like chain (TSLPR- gamma ) and a common interleukin 7 (IL-7) R alpha chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7R alpha chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signalling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc tag

This recombinant protein can be used for biological assays. For research use only.