Anti-ZNF521 Rabbit Polyclonal Antibody
PRSI6859
- Antigen name:Zinc Finger Protein 521
- Antigen symbol:ZNF521
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:ZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521.
- Tested applications:E, WB, ICC, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Type:
Antigen: ZNF521
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human