Specifications
- Antibody type:Primary
- Antigen name:Protein Kinase, AMP-activated Non-catalytic Subunit Beta 1
- Antigen symbol:PRKAB1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Gene ID:5564
- Antigen synonyms:kinase AMPK-beta1|AMPK-beta1|AMPK beta-1 chain|5'-AMP-activated protein kinase beta-1 subunit|PRKAB1|AAKB1
- Storage buffer:Aqueous buffered solution containing 100 μg/ml BSA, 50% glycerol and 0,09% sodium azide. Store at −20 °C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4 °C
- Immunogen:238-270/270
- Purification:Purified by Protein A
- Size:100 μl
- Pk:100 µl
Specifications
About this item
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Recommended Dilutions: Western Blot: 1:100 to 1000; IHC-P: 1:100 to 500; IF(IHC-P): 1:50 to 200.
Type: Primary
Antigen: PRKAB1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat