Specifications
- Antibody type:Primary
- Antigen name:Beta-nerve growth factor
- Antigen symbol:beta NGF
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Sheep
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Birds,Human,Rat,Mouse
- Western blot:Yes
- Epitope:Multiple points of reactivity likely because of the polyclonal nature of the antibody
- Cross adsorption:No
- Neutralisation:Yes
- Format:Lyophilized
- Immunogen:Native mouse beta NGF purified from submaxillary salivary gland (95% purity by PAGE)
- Size:500 µg
- Pk:500 µG
Specifications
About this item
FUNCTION: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SUBUNIT: Homodimer, associated by noncovalent forces. SUBCELLULAR LOCATION: Secreted protein. SIMILARITY: Belongs to the NGF-beta family.
A cross reactivity of less than 1% to recombinant human BDNF, NT3, NT4/5 by ELISA has been shown.
Application Information:
IHC, 1-site ELISA, WB, immunoblot, inhibition of biological activity. A concentration of 1-3 µg/ml is recommended for IHC, western blot and immunoblot, ELISA, inhibition of biological activity in vitro. Use neat for in vivo studies at 2-10 µg/ml (ED50). This antiserum completely inhibits neuronal survival and the outgrowth actions of murine NGF in chicken DRG in vitro. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: beta NGF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Multiple points of reactivity likely because of the polyclonal nature of the antibody
Host: Sheep
Isotype: IgG
Reactivity: Mouse, Rat, Human, Avis