You searched for: Y-27632

Supplier: Merck Millipore (Calbiochem‎)

A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140 nm for p160ROCK). Also inhibits ROCK-II with equal potency. Also acts as a potent inhibitor of agonist-induced Ca²⁺ sensitization of myosin phosphorylation and smooth muscle contraction.