You searched for: Proteins and Peptides

Supplier: Thermo Fisher Scientific

CAS No.: 1116-22-9

Supplier: Novus Biologicals

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human COL5A1.

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus Nucleocapsid (core) 22kDa, Fluorescein

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus NS3 Genotype-6 (1356-1459)

Supplier: Apollo Scientific

Recombinant Hepatitis A Virus VP1-P2A (722-830)

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus NS3 Genotype-1b (1356-1459)

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus NS3 Genotype-2b (1356-1459)

Supplier: Apollo Scientific

Recombinant Hepatitis C Virus NS3 Genotype-2c (1192-1459)

Supplier: Thermo Fisher Scientific

Buffer with a useful pH range 7,5 to 8,9

Supplier: AGILENT

Purified ribonuclease inhibitor tested to be free of contaminating activity for the degradation of nucleic acids.

Supplier: Apollo Scientific

Human Recombinant Epidermal Growth Factor Receptor (from Sf9 cells)

Supplier: Apollo Scientific

Inhibitor of aspartyl proteases, particularly effective onHIV-I proteinase and HIV-II proteinase

Supplier: Apollo Scientific

Recombinant HuSCF produced in E.coli, lypohilized powder >95% (HPLC, SDS-PAGE)

Supplier: Novus Biologicals

A recombinant protein with a C-terminal his-tag and corresponding to the amino acids 1 - 298 of human CDK2.

Supplier: Aviva Systems Biology

TickBorne Encephalitis virus NS1 contains a C-terminal 6x his-tag with protein range 773 to 1128aa.

Supplier: Apollo Scientific

Human Recombinant Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 1

Supplier: OriGene

Recombinant protein of human protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform (PPM1B), transcript variant 2, 100 µg.

Supplier: Apollo Scientific

Recombinant HuB2M produced in E. coli, sterile clear liquid, 1mg/mg, >95% (HPLC, SDS-PAGE)

Supplier: TCI

Melting point: 158 °C
Specific rotation [a]20/D: –7° (C=5, H₂O)
Water: Max. 8,0%
Purity (nonaqueous titration): Min. 98,0% (calculated on anhydrous substance)

Supplier: Shenandoah Biotechnology

IL-7 promotes the stimulation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. IL-7, along with IL-2, 15, and 21, is a member of the common gamma (γc) chain cytokine family.

Supplier: OriGene

Purified recombinant protein of S. pyogenes Cas9 endonuclease (Cas9) containing Simian virus 40 (SV40) T antigen nuclear localisation sequence (NLS) on the N- and C- termini of the protein., with N-terminal HIS tag, expressed in E.coli, sterile-filtered, suitable for cell culture.

Supplier: Shenandoah Biotechnology

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signaling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3).

Supplier: ProSci Inc.

Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.

Supplier: BIOWEST

Bovine serum albumin (BSA) is commonly used in cell culture protocols, particularly where protein supplementation is necessary and the other components of serum are unwanted. In cell culture, its main role is as a carrier of small molecules. Because of its negative charge, BSA binds water, salts, fatty acids, vitamins and hormones, then carries these bound components between tissues and cells. The binding capacity also makes BSA an effective scavenger to remove toxic substances, including pyrogens, from the medium.

Supplier: Shenandoah Biotechnology

Cytokines for polarizing mouse T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. Although the exact function of IL-9 producing T cells is yet to be completely clear it is proposed that these cells could be important in inflammation and helminth infections. Th9 cells can be generated from naive CD4+ T cells in culture by culturing them in the presence of IL-4 and TGF-β 1. It also appears that IFNγ and IL-27 can inhibit the generation of Th9 cells.

Supplier: ProSci Inc.

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

Supplier: Shenandoah Biotechnology

Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatised tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

Supplier: Shenandoah Biotechnology

Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.

Supplier: Shenandoah Biotechnology

Interleukin 34 (IL-34) was originally identified in humans, by large scale screening of secreted proteins; orthologs have also been found in chimpanzee, murine, rat and chicken. Human IL-34 is synthesized as a 242 amino acid (aa) precursor that contains a 20 aa signal sequence and a 222 aa mature chain. IL-34 is secreted as a homodimer and contains one potential N-glycosylation site.  IL-34 increases proliferation of immune cells known as monocytes; it elicits its activity by binding the Colony Stimulating Factor 1 Receptor (CSF-1R). Expression of IL-34 is most abundant in the spleen and is expressed in many other tissues including the heart, brain, liver, kidney, thymus, intestine and lung. Human IL-34 contains a C-terminal 6x-polyhistidine (6xHis) tag.