You searched for: Proteins and Peptides

Supplier: Biorbyt

Human recombinant Kallikrein 7 (from HEK293 cells)

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Rhesus macaque recombinant IL3 (from E. coli)

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Human recombinant HBP (from HEK293 cells)

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Human recombinant CD99 (from HEK293 cells)

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Human recombinant nepmucin (from HEK293 cells)

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Human recombinant CST2 (from HEK293 cells)

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Human recombinant TrkB (from HEK293 cells)

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Human VEGF receptor-3 (from Insect cells)

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Human recombinant IL20Ralpha (from HEK293 cells)

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Human recombinant KRT8 GST (from E. coli)

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Human VEGF receptor 1 (from Insect cells)

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Human recombinant CSH1 (from HEK293 cells)

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Human recombinant THSD1 (from HEK293 cells)

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Human recombinant BSSP4 (from HEK293 cells)

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Human recombinant AGR3 (from HEK293 cells)

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Human recombinant PAI1 (from HEK293 cells)

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Human Recombinant CD200 (from HEK293 cells)

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Human recombinant CD306 (from HEK293 cells)

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Human recombinant CD5L (from HEK293 cells)

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Human recombinant CD40 (from HEK293 cells)

Supplier: STEMCELL TECHNOLOGIES

R-Spondin-1 (RSPO1) is the prototype member of the R-Spondin (RSPO) protein subfamily of a superfamily of thrombospondin type 1 repeat (TSR-1)-containing proteins (Chen et al.; Kamata et al.; Kazanskaya et al.; Kim et al.). Although unable to initialize signaling, RSPO family members are potent enhancers of WNT signaling (Cruciat and Niehrs; de Lau et al.; Kamata et al.; Kazanskaya et al.). They are characterized by a TSR-1 domain, a carboxy-terminal region with positively charged amino acids, and two N-terminal furin-like cysteine-rich repeats (Glinka et al.; Kazanskaya et al.). R­-Spondin-1 activates β­-catenin signaling via the WNT signaling cascade and by indirectly increasing low-density lipoprotein receptor-related protein 6 (LRP6) on the cell surface. It does this by binding leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), and competing with WNT antagonist DKK­1 for binding to the WNT co­receptors, Kremen and LRP­6, which reduces DKK­1-­mediated internalization of LRP6 (Binnerts et al.). RSPO1 is involved in a wide range of pleiotropic roles during embryogenesis, it is required for the specification of hematopoietic stem cells, and it has been shown to be important in the growth, survival, and migration of ovarian cancer cells (Cruciat and Niehrs; de Lau et al.; Genthe and Clements; Liu et al.).

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Human PTH (7-34) (from E. coli)

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Human recombinant TRAILR2 (from HEK293 cells)

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HIV-1 p24c Sf9 (from Baculovirus (insect cells))

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Human angiopoietin-like 4 HEK (from HEK293 cells)

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Human VEGFR2 Fc Chimera (from insect cells)

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Dog recombinant apoliprotein HEK (from HEK293 cells)

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Human recombinant serpin A3 (from HEK293 cells)

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Human recombinant Kallikrein 13 (from HEK293 cells)

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Human recombinant CD3 epsilon (from HEK293 cells)