You searched for: N-Hexanoyl-D-erythro-sphingosine

Supplier: Apollo Scientific

A biologically active, cell permeable, nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10nM & activiates MAP kinase.

Supplier: ENZO LIFE SCIENCES

A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.