Specifications
- Antibody type:Primary
- Antigen name:C11ORF46
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Epitope:21-120/260
- Form:Liquid
- Gene ID:120534
- Antigen synonyms:Uncharacterized protein C11orf46|DJ299F11.1|AL14E_HUMAN|Hypothetical protein LOC120534|Chromosome 11 open reading frame 46|FLJ38968
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human C11ORF46
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
C11orf46, also known as FLJ38968 or dJ299F11.1, is a 260 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumours, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Type: Primary
Antigen: C11ORF46
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/260
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat