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Anti-5 MethylCytosine Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-5 MethylCytosine Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-9450R-A750
Supplier:  Bioss
Anti-5 MethylCytosine Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-9450R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    5 MethylCytosine
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western blot:
    Yes
  • Form:
    Liquid
  • Antigen synonyms:
    5 mC|5-MethylCytidine|5 Me Cytidine|5 MeCyd|5 MethylCytosine|5-mC|5-Me Cytidine|5-Methyl-Cytosine|5 me C|5 Methyl Cytidine|5 m C|5-Methyl Cytidine
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated 5 MethylCytosine
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.

Type: Primary
Antigen: 5 MethylCytosine
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Others