Specifications
- Antibody type:Primary
- Antigen name:ATAD3A
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Epitope:351-450/634
- Form:Liquid
- Gene ID:55210
- Antigen synonyms:Atad3a|ATPase family AAA domain containing protein 3B|ATPase family, AAA domain containing, member 3B|ATPase family, AAA domain containing 3B|ATAD3C|ATD3A_HUMAN|ATPase family AAA domain containing protein 3A|FLJ35514|TOB3|AAA-TOB3|ATPase family, AAA domain containing 3A|ATAD3B|AAA ATPase TOB3|AAA-ATPase TOB3|ATAD3A/B/C|ATPase family AAA domain-containing protein 3|FLJ10709
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ATAD3A
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The AAA ATPase family of molecular chaperones are characterised by a highly conserved AAA motif. Composed of 200-250 residues, the AAA domain contains Walker homology sequences and imparts ATPase activity. Members of the AAA ATPase family act as DNA helicases as well as transcription factors and are thought to be involved in several cellular functions such as cell-cycle regulation, protein proteolysis, organelle biogenesis and vesicle-mediated protein transport. Mitochondrial membrane proteins ATAD3A and ATAD3B contribute to the stabilisation of nucleoids which are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
Type: Primary
Antigen: ATAD3A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 351-450/634
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat