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Anti-IRE1a Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-IRE1a Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-8680R-A680
Supplier:  Bioss
Anti-IRE1a Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-8680R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    IRE1a
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Pig,
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Epitope:
    252-260/977
  • Form:
    Liquid
  • Gene ID:
    2081
  • Antigen synonyms:
    Serine/threonine-protein kinase/endoribonuclease IRE1|Endoplasmic reticulum-to-nucleus signaling 1|Inositol-requiring protein 1|hIRE1p|Ire1-alpha|IRE1P|IRE1a|ERN1|IRE1
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    105 kDa
  • Storage temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human IRE1a
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Type: Primary
Antigen: IRE1a
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 252-260/977
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Pig