Anti-IRE1a Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-8680R-A680
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:IRE1a
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Pig,Human,Rat,Mouse
- Western blot:Yes
- Epitope:252-260/977
- Form:Liquid
- Gene ID:2081
- Antigen synonyms:Serine/threonine-protein kinase/endoribonuclease IRE1|Endoplasmic reticulum-to-nucleus signaling 1|Inositol-requiring protein 1|hIRE1p|Ire1-alpha|IRE1P|IRE1a|ERN1|IRE1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:105 kDa
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human IRE1a
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Type: Primary
Antigen: IRE1a
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 252-260/977
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Pig