- Antibody type:Primary
- Antigen name:NDEL1 Ser231
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Form:Liquid
- Gene ID:81565
- Antigen synonyms:NUDE like protein|NDEL1phospho S231|A. nidulans|Mitosin associated protein MITAP1|NudE nuclear distribution gene E homolog like 1|Mitosin associated protein 1|Nuclear distribution protein nudE-like 1|MITAP 1|NudE nuclear distribution gene E homolog like 1 A. nidulans|Nuclear distribution protein nudE like 1|NDEL1_HUMAN|MITAP1|DKFZp451M0318|EOPA|Ndel 1|Protein Nudel|Nuclear distribution gene E like homolog 1|Mitosin-associated protein 1|NUDEL|Ndel1|Nudelphospho S231|ENDOOLIGOPEPTIDASE A
- Modification:Phosphorylation (Ser231)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:38 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser231
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Nudel is important for normal cortical development. It is invovled in microtubule organisation, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50% identity with mouse and human NUDE proteins.
Type: Primary
Antigen: NDEL1 Ser231
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Rat