Anti-eIF2 alpha subunit 1 Ser52 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-4842R-A750
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:eIF2 alpha subunit 1 Ser52
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Gene ID:1965
- Antigen synonyms:EIF2|EIF-2alpha|EIF-2A|EIF2A|eIF-2-alpha|Eukaryotic translation initiation factor 2 subunit alpha|EIF-2|Eukaryotic translation initiation factor 2 subunit 1|EIF2S1
- Modification:Phosphorylation (Ser52)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:36 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human eIF2 alpha subunit 1 around the phosphorylation site of Ser52 [EL(p-S)RR]
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyse another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalysed by eIF-2B.
Type: Primary
Antigen: eIF2 alpha subunit 1 Ser52
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat