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Anti-ERN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Anti-ERN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Catalog # BOSSBS-4308R-FITC
Supplier:  Bioss
Anti-ERN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Catalog # BOSSBS-4308R-FITC
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Endoplasmic reticulum to nucleus signaling 1
  • Antigen symbol:
    ERN1
  • Clonality:
    Polyclonal
  • Conjugation:
    FITC (Fluorescein Isothiocyanate)
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    2081
  • Antigen synonyms:
    ER to nucleus signalling 1|inositol-requiring 1|protein kinase/endoribonuclease|endoplasmic reticulum to nucleus signaling 1|IRE1P|MGC163279|endoplasmic reticulum to nucleus signalling 1|IRE1a|IRE1-alpha|MGC163277|ERN1|IRE1|FLJ30999
  • Modification:
    phospho-Ser726
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Storage temperature:
    Store at 4°C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Immunogen:
    700-750/977
  • Purification:
    Purified by Protein A
  • Pk:
    100 µl

Specifications

About this item

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ERN1
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human