Specifications
- Antibody type:Primary
- Antigen name:CACH6/Cav2.3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Epitope:1265-1360/2313
- Form:Liquid
- Gene ID:777
- Antigen synonyms:Calcium channel, L type, alpha 1 polypeptide, isoform 6|CACNA1E|Cav 2.3|Voltage gated calcium channel subunit alpha Cav2.3|Cchra 1|CACNL1A6|CACH 6|BII|CAC 1E|calcium channel, R type|Voltage dependent R type calcium channel subunit alpha 1E|CACH6|Cchra1|Cacnl1 a6|Brain calcium channel II|CAC1E
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:262 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Cav23
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the 'high voltage-activated' group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.
Type: Primary
Antigen: CACH6/Cav2.3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1265-1360/2313
Host: Rabbit
Isotype: IgG
Reactivity: Human