Specifications
- Antibody type:Primary
- Antigen name:GGA3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:51-150/723
- Form:Liquid
- Gene ID:23163
- Antigen synonyms:ADP-ribosylation factor-binding protein GGA3|ARF-binding protein 3|gamma ear-containing|ADP ribosylation factor binding protein 3|ADP ribosylation factor binding protein GGA3|GGA 3|GGA3_HUMAN|ARF binding protein GGA3|Golgi localized gamma ear containing ARF binding protein 3|Golgi associated gamma adaptin ear containing ARF binding protein 3|ARF binding protein GGA 3|KIAA0154|ADP ribosylation factor binding protein GGA 3|GGA3|Golgi-localized
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:78 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human GGA3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.
Type: Primary
Antigen: GGA3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/723
Host: Rabbit
Isotype: IgG
Reactivity: