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Anti-GGA3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-GGA3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13345R-A680
Supplier:  Bioss
Anti-GGA3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13345R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    GGA3
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Western blot:
    Yes
  • Epitope:
    51-150/723
  • Form:
    Liquid
  • Gene ID:
    23163
  • Antigen synonyms:
    ADP-ribosylation factor-binding protein GGA3|ARF-binding protein 3|gamma ear-containing|ADP ribosylation factor binding protein 3|ADP ribosylation factor binding protein GGA3|GGA 3|GGA3_HUMAN|ARF binding protein GGA3|Golgi localized gamma ear containing ARF binding protein 3|Golgi associated gamma adaptin ear containing ARF binding protein 3|ARF binding protein GGA 3|KIAA0154|ADP ribosylation factor binding protein GGA 3|GGA3|Golgi-localized
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    78 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human GGA3
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.

Type: Primary
Antigen: GGA3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/723
Host: Rabbit
Isotype: IgG
Reactivity: