Specifications
- Antibody type:Primary
- Antigen name:G6PC3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Epitope:201-300/346
- Form:Liquid
- Gene ID:92579
- Antigen synonyms:Ubiquitous glucose-6-phosphatase catalytic subunit-related protein|Glucose 6 phosphatase, catalytic, 3|G-6-Pase 3|G6Pase 3|SCN4|UGRP|Glucose-6-phosphatase 3|Glucose-6-phosphatase beta|G6Pase-beta
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:39 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human G6PC3
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).
Type: Primary
Antigen: G6PC3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-300/346
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat