Specifications
- Antibody type:Primary
- Antigen name:FOXI1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Epitope:101-200/378
- Form:Liquid
- Gene ID:2299
- Antigen synonyms:FKHL10|Forkhead related activator 6|FREAC 6|HFH 3|FREAC6|Forkhead box I1|HNF-3 fork-head homolog 3|HFH3|FOXI1_HUMAN|Hepatocyte nuclear factor 3 forkhead homolog 3|Forkhead-related protein FKHL10|Forkhead like 10|Forkhead related transcription factor 6|Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds|HNF 3/fork head homolog 3|FKH10|MGC34197|Forkhead box protein I1|Forkhead Drosophila like 10
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:41 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human FOXI1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
FOXI1 is a member of the FOX family of transcription factors. The FOX family is a large group of proteins (consisting of at least 43 members) that share a common DNA binding domain termed winged-helix or forkhead domain. FOX transcription factors play important roles in development, differentiation, aging and hormone responsiveness. Localizing to the nucleus, FOXI1 functions as a transcription factor. Mice with mutated forms of FOXI1 show defects in ear development, implying that FOXI1 plays a significant role in the developmental pathway of ears and, in particular, the cochlea and vestibulum. FOXI1 is an upstream transcription regulator of Pendrin (a protein associated with deafness), suggesting a role for FOXI1 in the pathogenesis of Pendred syndrome (PS), a condition of nonsyndromic hearing loss and enlarged vestibular aqueduct (EVA).
Type: Primary
Antigen: FOXI1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 101-200/378
Host: Rabbit
Isotype: IgG
Reactivity: