Order Entry
Finland
ContactUsLinkComponent
Anti-MAPK6/ERK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-MAPK6/ERK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-12405R-A750
Supplier:  Bioss
Anti-MAPK6/ERK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-12405R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    MAPK6/ERK3
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Mouse
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Epitope:
    21-120/721
  • Form:
    Liquid
  • Gene ID:
    5597
  • Antigen synonyms:
    Protein kinase mitogen activated 5|MAPK 6|Extracellular signal regulated kinase 3|PRKM6|Mitogen activated protein kinase 6|Protein kinase mitogen activated 6|p97 MAPK|MAP kinase isoform p97|ERK 3|ERK3|MAPK6|Mitogen-activated protein kinase 6|p97-MAPK|ERK-3|Extracellular signal-regulated kinase 3|MK06_HUMAN|MAP kinase 6|Extracellular signal regulated kinase p97
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    83 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human MAPK6/ERK3
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Mitogen-activated protein kinase (MAPK) Signalling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 Signalling pathways. Despite lacking a definitive nuclear localisation sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.

Type: Primary
Antigen: MAPK6/ERK3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/721
Host: Rabbit
Isotype: IgG
Reactivity: Mouse