Specifications
- Antibody type:Primary
- Antigen name:MAPK6/ERK3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:21-120/721
- Form:Liquid
- Gene ID:5597
- Antigen synonyms:Protein kinase mitogen activated 5|MAPK 6|Extracellular signal regulated kinase 3|PRKM6|Mitogen activated protein kinase 6|Protein kinase mitogen activated 6|p97 MAPK|MAP kinase isoform p97|ERK 3|ERK3|MAPK6|Mitogen-activated protein kinase 6|p97-MAPK|ERK-3|Extracellular signal-regulated kinase 3|MK06_HUMAN|MAP kinase 6|Extracellular signal regulated kinase p97
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:83 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human MAPK6/ERK3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Mitogen-activated protein kinase (MAPK) Signalling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 Signalling pathways. Despite lacking a definitive nuclear localisation sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
Type: Primary
Antigen: MAPK6/ERK3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/721
Host: Rabbit
Isotype: IgG
Reactivity: Mouse