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Anti-BCL9 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Anti-BCL9 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Catalog # BOSSBS-12393R-HRP
Supplier:  Bioss
Anti-BCL9 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Catalog # BOSSBS-12393R-HRP
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    B-Cell CLL/Lymphoma 9
  • Antigen symbol:
    BCL9
  • Clonality:
    Polyclonal
  • Conjugation:
    HRP (Horseradish Peroxidase)
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    101060700
  • Antigen synonyms:
    B-cell CLL/lymphoma 9|BCL9_HUMAN.|B-cell CLL/lymphoma 9-like|DLNB11|LGS|BCL-9|BCL 9|Legless homolog
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
  • Storage temperature:
    Store at 4°C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Pk:
    100 µl

Specifications

About this item

Bcl-9L is a 1,499 amino acid protein that localizes to the nucleus and contains a specialized C-terminal domain that is important for its overall activity. Expressed in breast tissue, as well as in eye, lung, prostate and various carcinomas, Bcl-9L functions as a transcriptional activator that forms a complex with Parafibromin and β-catenin and is thought promote the transcriptional activity of Parafibromin and enhance the neoplastic transforming activity of β-catenin. Bcl-9L exists as multiple alternatively spliced isoforms and is thought to be involved in tumorigenesis, possibly playing a role in tumor transformation and metastasis. The gene encoding Bcl-9L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: BCL9
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat