Specifications
- Antibody type:Primary
- Antigen name:GABRA6/GABA A Receptor alpha 6
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:85-180/453
- Form:Liquid
- Gene ID:2559
- Antigen synonyms:GABRA 6|GABAA receptor subunit alpha-6|Gamma-aminobutyric acid receptor subunit alpha-6|Gamma aminobutyric acid A receptor alpha 6|GABA subunit A receptor alpha 6|Gamma aminobutyric acid receptor subunit alpha 6|MGC116904|GABRA6|GABA A Receptor alpha 6 polypeptide|GABA A receptor subunit alpha 6|MGC116903|GABA A receptor alpha 6|GBRA6_HUMAN|GABA A|Gamma aminobutyric acid GABA A receptor alpha 6
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:49 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyse the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R gamma 1-3, GABAA R gamma , GABAA R delta. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Type: Primary
Antigen: GABRA6/GABA A Receptor alpha 6
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 85-180/453
Host: Rabbit
Isotype: IgG
Reactivity: