- Antibody type:Primary
- Antigen name:V-Akt Murine Thymoma Viral Oncogene Homolog 1
- Antigen symbol:AKT1
- Clonality:Polyclonal
- Conjugation:HRP (Horseradish Peroxidase)
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Gene ID:24185
- Antigen synonyms:AKT2|RAC|RAC-gamma serine/threonine-protein kinase|PKB-GAMMA|RAC-BETA|PKBG|kinase Akt1|Murine thymoma viral (v-akt) homolog-2|rac protein kinase beta|Protein kinase B beta|PKBB|RAC-PK-beta|EC 2.7.11.1|PKB|AKT|RAC-PK-gamma|PKB beta|RAC-PK-alpha|AKT1 kinase|RAC-beta serine/threonine-protein kinase|C-AKT|RAC-gamma serine/threonine protein kinase|v-akt murine thymoma viral oncogene homolo|PKB gamma|STK-2|Protein kinase B|PRKBB|PKBBETA|PKB-alpha|RAC-gamma|PRKBG|Protein kinase Akt-2|RAC-alpha serine/threonine kinase
- Modification:phospho-Ser472/Ser473/Ser474
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:450-480/480
- Purification:Purified by Protein A
- Pk:100 µl
AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: AKT1
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat