381 Results for: "mek1"

Supplier: Bioworld Technology

Synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Threonine 292.

Supplier: Bioworld Technology

Synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Threonine 286.

Supplier: ANTIBODIES.COM

Rat MEK1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat MEK1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Biorbyt

Anti-MEK1/2 Rabbit Polyclonal Antibody

Supplier: Bioworld Technology

Synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Serine 222.

Supplier: ANTIBODIES.COM

Human MEK1 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human MEK1 in serum, plasma, and other biological fluids.

Supplier: Abcam

Anti-MEK1 + MEK2 (phospho S222) Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-MEk1/2 Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-MEk1/2 Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-MEk1/2 Rabbit Polyclonal Antibody

Supplier: Bioss

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyse the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Bioworld Technology

Synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Serine 218.

Supplier: Bioss

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyse the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Bioss

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyse the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Biorbyt

Anti-MEk1/2 Rabbit Polyclonal Antibody

Supplier: OriGene

Anti-MEK1 Rabbit Polyclonal Antibody

Supplier: Abcam

Rabbit monoclonal [EPR3338] to MEK1 (phospho S298).

Supplier: Biorbyt

Anti-MEK1/2 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-MEK1, MEK2 Rabbit Monoclonal Antibody [clone: 7H39]

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to MEK1 for WB and ICC/IF with samples derived from human, mouse and rat.

Supplier: Bioss

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyse the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade. Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements. One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis. MAP2K1/MEK1 has been shown to export PPARG from the nucleus. The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Abcam

Rabbit monoclonal [EPR2365Y] to MEK1 (phospho T292).

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to MEK1 for WB and IHC with samples derived from human.

Supplier: Abcam

Rabbit monoclonal [EP2364Y] to MEK1 (phospho T286).

Supplier: ENZO LIFE SCIENCES

MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to MEK1 for WB and IHC with samples derived from Human, Mouse and Rat.

Supplier: Biorbyt

Anti-MEK1/MEK2 Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-MEK1/MEK2 Rabbit Polyclonal Antibody

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to MEK1 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to MEK1 + MEK2 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.