22612 Results for: "boots+cover&pageNo=11&view=list"
Anti-STK11 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Bioss
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
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TUBING ARMAFLEX TYPE:D 10 1 * 1 m
Supplier: LAUDA
TUBING ARMAFLEX TYPE:D 10 1 * 1 m
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2,3-DINOR-11Β-PROSTAGLANDIN F2Α-D9 1 * 50 µG
Supplier: Cayman Chemical
2,3-DINOR-11Β-PROSTAGLANDIN F2Α-D9 1 * 50 µG
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Magnetic hotplate stirrer, RCT basic
Supplier: IKA
The RCT basic magnetic stirrer provides reliability, an exceptionally long product lifetime and the highest safety standards. RCT basic is suitable for stirring tasks up to 20 L (H₂O) and reaches temperatures up to 310 °C. With the connection option for an external temperature sensor (PT1000.60), the temperature can be measured and controlled directly in the reaction medium. Thanks to insulation of the aluminium heating plate, maintenance-free EC motor and electronic switching power supply, RCT basic features excellent energy efficiency as well as reduced self-heating of the heating plate during stirring operation, contributing to a more sustainable laboratory.
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2-(diethylphosphonatoamino)-1,1,1,3,3,3-hexafluoro-2-(N1-phenylhydrazine-1-carbothioamido)propane, TECH 1 * 250 mg
Supplier: Thermo Scientific
2-(diethylphosphonatoamino)-1,1,1,3,3,3-hexafluoro-2-(N1-phenylhydrazine-1-carbothioamido)propane, TECH 1 * 250 mg
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Melting crucibles 79, shallow 1 * 10 items
Supplier: Roth Carl
Melting crucibles 79, shallow 1 * 10 items
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Rotilabo-universal indicator paper type 1 * 1 items
Supplier: Roth Carl
Rotilabo-universal indicator paper type 1 * 1 items
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Sekuroka-nitrile gloves Camatril 1 * 2 PAIR
Supplier: Roth Carl
Sekuroka-nitrile gloves Camatril 1 * 2 PAIR
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GLOVE CUTTING 6300 GR L 1 * 100 PAIR
Supplier: AS ARBEITSSCHUTZ
GLOVE CUTTING 6300 GR L 1 * 100 PAIR
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Filter paper folded MN 611 1/4 11cm diameter, pack of 100. 1 * 100 items
Supplier: MACHEREY-NAGEL
Filter paper folded MN 611 1/4 11cm diameter, pack of 100. 1 * 100 items
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SANDAL HAMBURG WHITE SIZE 43 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 43 1 * 1 PAIR
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11β-13,14-dihydro-15-keto Prostaglandin F2α-d9 1 * 50 µG
Supplier: Cayman Chemical
11β-13,14-dihydro-15-keto Prostaglandin F2α-d9 1 * 50 µG
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Sekuroka-nitrile gloves Camatril 1 * 2 PAIR
Supplier: Roth Carl
Sekuroka-nitrile gloves Camatril 1 * 2 PAIR
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Rotilabo-aluminium caps with septum 1 * 200 items
Supplier: Roth Carl
Rotilabo-aluminium caps with septum 1 * 200 items
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CASE GKK252 PLASTIC 235X185X48MM 1 * 1 items
Supplier: Greisinger
CASE GKK252 PLASTIC 235X185X48MM 1 * 1 items
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GLOVES NYLOTEX 7 NITRAS 3520 1 * 12 PAIR
Supplier: AS ARBEITSSCHUTZ
GLOVES NYLOTEX 7 NITRAS 3520 1 * 12 PAIR
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Aqueous Ethanol Standard (0.5 g/l) 10 x 1.2 mL 1 * 10 items
Supplier: LGC Standards PROMOCHEM
Aqueous Ethanol Standard (0.5 g/l) 10 x 1.2 mL 1 * 10 items
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Leather Glove HexArmor Chrome Series 4080 size XXL 1 * 1 PAIR
Supplier: UVEX
Leather Glove HexArmor Chrome Series 4080 size XXL 1 * 1 PAIR
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Electronic overhead stirrers, EUROSTAR 20 digital, EUROSTAR 20 high speed digital and EUROSTAR 40 digital
Supplier: IKA
Laboratory stirrers designed for simple stirring tasks for quantities up to 15 or 25 L (EUROSTAR 20 digital and EUROSTAR 40 digital), or for intensive stirring tasks for quantities up to 20 L (EUROSTAR 20 high speed digital). Units automatically adjust the speed through microprocessor controlled technology within the speed range of 0/30 to 2000 min⁻¹ (or 0/150 to 6000 for the high speed model). Safety circuits ensure automatic cut off in anti-stall or overload conditions. The actual shaft speed and preset speed are constantly monitored and variations are adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.
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Rain jackets, 3-in-1 Bomber, F465
Supplier: Portwest
Versatile and comfortable protection against all weather conditions. The detachable fur lining and collar, in combination with the zip-out sleeves, prove this is a superbly adaptable garment. Numerous zipped outer and interior pockets afford excellent personal security. Two-way zip for quick and easy access.
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Hose waste drain, EPDM L=1,8m 1 * 1 items
Supplier: BUCHI
Hose waste drain, EPDM L=1,8m 1 * 1 items
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SANDAL HAMBURG WHITE SIZE 40 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 40 1 * 1 PAIR
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SANDAL HAMBURG WHITE SIZE 46 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 46 1 * 1 PAIR
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SANDAL HAMBURG WHITE SIZE 41 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 41 1 * 1 PAIR
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Anti-STK11 Rabbit Polyclonal Antibody
Supplier: Bioss
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
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Filter paper circles MN 605 11cm diameter, pack of 100. 1 * 100 items
Supplier: MACHEREY-NAGEL
Filter paper circles MN 605 11cm diameter, pack of 100. 1 * 100 items
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SANDAL HAMBURG WHITE SIZE 45 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 45 1 * 1 PAIR
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SANDAL HAMBURG WHITE SIZE 42 1 * 1 PAIR
Supplier: SCHURR SCHUHVERTRIEB
SANDAL HAMBURG WHITE SIZE 42 1 * 1 PAIR
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connecting cable Combox 1 * 1 items
Supplier: HUBER
connecting cable Combox 1 * 1 items